Methyl-N-(5-[propan-2-yl)sulfanyl]-1H-benzimidazol-2-yl)carbamate

• CAT Number: C000275
• CAS Number: 108579-67-5
• Molecular Formula: C₁₂H₁₅N₃O₂S
• Molecular Weight: 265.33
• Purity: ≥95%
• Synonyms: Albendazole EP Impurity L
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
• Appearance: Off-White to Pale Brown Solid
• Storage: -20°C, Inert atmosphere

Methyl-N-(5-[propan-2-yl)sulfanyl]-1H-benzimidazol-2-yl)carbamate(CAT: C000275) holds significance in the field of pharmaceutical chemistry and parasitology. It is recognized as an impurity of Albendazole, an anthelmintic drug used to treat various parasitic infections. Additionally, it plays a role as a screening compound against Echinococcus granulosus cysts in mice, contributing to research on potential treatments for parasitic diseases.

Reference

Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008); Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009); Huang, L., et al.: Zhongguo Yiyao Gongye Zazhi, 26, 55-59 (1995)