Methylaervine

For research use only. Not for therapeutic Use.

  • CAT Number: I032122
  • CAS Number: 86293-40-5
  • Molecular Formula: C15H10N2O2
  • Molecular Weight: 250.25
  • Purity: 98%
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Methylaervine(Cat No.:I032122)is a synthetic compound belonging to the class of alkaloids and is chemically related to the plant-derived substance aervine. It has shown potential in biological research for its pharmacological effects, which may include antimicrobial, anticancer, or anti-inflammatory activities. While its precise mechanism of action is still under investigation, methylaervine is believed to interact with cellular pathways involved in immune responses and cell proliferation. Currently, it is primarily studied in preclinical settings to explore its therapeutic potential, particularly in treating various infectious and inflammatory diseases. Its safety and efficacy are still being evaluated in clinical trials.


Catalog Number I032122
CAS Number 86293-40-5
Synonyms

Methylaervine; NSC-341584; NSC341584; NSC 341584; 10-methoxycanthine-6-one;

Molecular Formula C15H10N2O2
Purity 98%
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 12-methoxy-1,6-diazatetracyclo[7.6.1.05,16.010,15]hexadeca-3,5(16),6,8,10,12,14-heptaen-2-one
InChI InChI=1S/C15H10N2O2/c1-19-9-2-4-13-11(8-9)10-6-7-16-12-3-5-14(18)17(13)15(10)12/h2-8H,1H3
InChIKey FDBMONUDUKGKGY-UHFFFAOYSA-N
SMILES COC1=CC2=C(C=C1)N3C(=O)C=CC4=NC=CC2=C43
Reference

1: Dan W, Gao J, Li L, Xu Y, Wang J, Dai J. Cellular and non-target metabolomics approaches to understand the antifungal activity of methylaervine against Fusarium solani. Bioorg Med Chem Lett. 2021 Apr 26;43:128068. doi: 10.1016/j.bmcl.2021.128068. Epub ahead of print. PMID: 33915256.
2: Bharitkar YP, Hazra A, Apoorva Poduri NS, Ash A, Maulik PR, Mondal NB. Isolation, structural elucidation and cytotoxicity evaluation of a new pentahydroxy-pimarane diterpenoid along with other chemical constituents from Aerva lanata. Nat Prod Res. 2015 Feb;29(3):253-61. doi: 10.1080/14786419.2014.971794. Epub 2014 Oct 28. PMID: 25348942.
3: Goyal M, Pareek A, Nagori BP, Sasmal D. Aerva lanata: A review on phytochemistry and pharmacological aspects. Pharmacogn Rev. 2011 Jul;5(10):195-8. doi: 10.4103/0973-7847.91120. PMID: 22279378; PMCID: PMC3263055.

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