Methylbenactyzium Bromide

• CAT Number: I013131
• CAS Number: 3166-62-9
• Molecular Formula: C₂₁H₂₈BrNO₃
• Molecular Weight: 422.36
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO: 6 mg/mL
• IUPAC Name: diethyl-[2-(2-hydroxy-2,2-diphenylacetyl)oxyethyl]-methylazanium;bromide
• InChI: InChI=1S/C21H28NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,24H,4-5,16-17H2,1-3H3;1H/q+1;/p-1
• InChIKey: DKMVJQCQTCLYIF-UHFFFAOYSA-M
• SMILES: CC[N+](C)(CC)CCOC(=O)C(C1=CC=CC=C1)(C2=CC=CC=C2)O.[Br-]

Methylbenactyzium bromide (Cat No.: I013131) is a synthetic anticholinergic compound that acts as a muscarinic acetylcholine receptor antagonist. It is primarily used to reduce gastrointestinal motility and secretions, making it effective in managing conditions like irritable bowel syndrome, peptic ulcers, and other spastic gastrointestinal disorders. By inhibiting parasympathetic nerve impulses, it helps relieve smooth muscle spasms and discomfort. Methylbenactyzium bromide’s peripheral action with minimal central nervous system effects makes it suitable for therapeutic use with a lower risk of neurological side effects.

Reference

[1]. Bhattacharjee AK, et al. Discovery of subtype selective muscarinic receptor antagonists as alternatives to atropine using in silico pharmacophore modeling and virtual screening methods. Bioorg Med Chem. 2013 May 1;21(9):2651-62. [2]. Nishikawa M, et al. Analysis of methylbenactyzium bromide in human urine by thin-layer chromatography and pyrolysis gas chromatography. Forensic Sci Int. 1991 Mar;49(2):197-203.