Methyldopa

• CAT Number: A000638
• CAS Number: 555-30-6
• Molecular Formula: C10H13NO4
• Molecular Weight: 211.2
• Purity: ≥95%
• Synonyms: 555-30-6; Alphamethyldopa; Aldomet; Alpha medopa; Dopamet
• Target: Neuronal Signaling
• Solubility: Soluble to 75 mM in DMSO
• Storage: -20°C
• InChI: 1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1
• InChIKey: CJCSPKMFHVPWAR-JTQLQIEISA-N
• SMILES: CC(CC1=CC(=C(C=C1)O)O)(C(=O)O)N

Methyldopa is a centrally acting antihypertensive agent. It is metabolized to alpha-methylnorepinephrine in the brain, and this compound activates central alpha-2 adrenergic receptors. Being a selective agonist for α2 adrenergic receptors, psychoactive drug is used as a sympatholytic or antihypertensive.

Reference

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