Methylstat

• CAT Number: M031580
• CAS Number: 1310877-95-2
• Molecular Formula: C28H31N3O6
• Molecular Weight: 505.56
• Purity: ≥95%
• Synonyms: methyl (E)-4-[hydroxy-[4-[[4-(naphthalen-1-ylcarbamoyloxymethyl)phenyl]methylamino]butyl]amino]-4-oxobut-2-enoate
• InChI: InChI=1S/C28H31N3O6/c1-36-27(33)16-15-26(32)31(35)18-5-4-17-29-19-21-11-13-22(14-12-21)20-37-28(34)30-25-10-6-8-23-7-2-3-9-24(23)25/h2-3,6-16,29,35H,4-5,17-20H2,1H3,(H,30,34)/b16-15+
• InChIKey: MUJOCHRZXRZONW-FOCLMDBBSA-N
• SMILES: COC(=O)/C=C/C(=O)N(CCCCNCC1=CC=C(C=C1)COC(=O)NC2=CC=CC3=CC=CC=C32)O

Methylstat（Cat No.:M031580）is a small molecule inhibitor used in epigenetics research, specifically targeting histone methyltransferases. It selectively inhibits the enzymatic activity of SETD7, an enzyme responsible for the methylation of lysine 4 on histone H3 (H3K4). By blocking this methylation, Methylstat disrupts gene expression regulation and cellular processes controlled by histone modifications. It is primarily used in studies focused on cancer biology, epigenetic regulation, and gene expression control. Methylstat offers a valuable tool for understanding the role of histone methylation in various diseases and may have potential therapeutic implications in epigenetic-based treatments.