For research use only. Not for therapeutic Use.
Methyltetrazine-acid (CAT: I016550) is a compound that contains a methyltetrazine moiety and an acidic group. The methyltetrazine group is commonly used in bioorthogonal chemistry for specific labeling and imaging applications. It can react with tetrazine-reactive probes or molecules through a rapid and highly selective bioorthogonal reaction, known as the inverse-electron-demand Diels-Alder (iEDDA) reaction. The resulting covalent linkage allows for the conjugation of various biomolecules, such as proteins or nucleic acids, to the methyltetrazine-acid compound, enabling targeted labeling, imaging, or drug delivery strategies in biological systems.
| Catalog Number | I016550 |
| CAS Number | 1380500-88-8 |
| Molecular Formula | C₁₁H₁₀N₄O₂ |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
