For research use only. Not for therapeutic Use.
Methyltetrazine-PEG5-triethoxysilane (CAT: I016537) is a PEG-based PROTAC linker designed for use in the synthesis of PROTAC molecules. PROTACs are a class of molecules that can selectively target and degrade specific proteins within cells. This linker contains a methyltetrazine group for bioorthogonal reactions, a PEG spacer to modulate the distance between the target protein and the E3 ligase ligand, and a triethoxysilane moiety for potential conjugation to surfaces or other molecules.
| Catalog Number | I016537 |
| CAS Number | 2353410-01-0 |
| Molecular Formula | C₂₉H₄₉N₅O₉Si |
| Purity | ≥95% |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
