Methysticin

• CAT Number: I002594
• CAS Number: 20697-20-5
• Molecular Formula: C15H14O5
• Molecular Weight: 274.27
• Purity: ≥95%
• Target: Cytochrome P450
• Solubility: 10 mM in DMSO
• Storage: 3 years -20℃ powder
• IUPAC Name: 2-[2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-2,3-dihydropyran-6-one
• InChI: InChI=1S/C15H14O5/c1-17-12-7-11(20-15(16)8-12)4-2-10-3-5-13-14(6-10)19-9-18-13/h2-6,8,11H,7,9H2,1H3
• InChIKey: GTEXBOVBADJOQH-UHFFFAOYSA-N
• SMILES: COC1=CC(=O)OC(C1)C=CC2=CC3=C(C=C2)OCO3

Methysticin (Cat.No:I002594) is a naturally occurring compound found in the roots of the kava plant (Piper methysticum). It is one of the major active ingredients responsible for the relaxing and sedative effects of kava. Methysticin has been traditionally used in Pacific Island cultures for its calming properties and as a ceremonial drink. Research suggests that methysticin may have potential as an anxiolytic and analgesic agent.

Reference

[1]. Li Y, et al. Methysticin and 7,8-dihydromethysticin are two major kavalactones in kava extract to induce CYP1A1. Toxicol Sci. 2011 Dec;124(2):388-99.