Metolazone-d7

• CAT Number: S000507
• CAS Number: 2714484-71-4
• Molecular Formula: C16H9D7ClN3O3S
• Molecular Weight: 372.88
• Purity: ≥95%
• IUPAC Name: 7-chloro-2-methyl-4-oxo-3-[2,3,4,5-tetradeuterio-6-(trideuteriomethyl)phenyl]-1,2-dihydroquinazoline-6-sulfonamide
• InChI: InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)/i1D3,3D,4D,5D,6D
• InChIKey: AQCHWTWZEMGIFD-HRDWIZOWSA-N
• SMILES: CC1NC2=CC(=C(C=C2C(=O)N1C3=CC=CC=C3C)S(=O)(=O)N)Cl

Metolazone-d7（Cat No.:S000507） is a deuterated form of metolazone, where seven hydrogen atoms are replaced with deuterium. Metolazone is a diuretic medication used primarily to treat high blood pressure and fluid retention (edema) associated with congestive heart failure or renal disease. The introduction of deuterium in Metolazone-d7 enhances the molecule’s metabolic stability, which is useful for detailed pharmacokinetic research. This improved stability allows researchers to more accurately study how metolazone is metabolized and eliminated from the body, facilitating the development of more effective dosing strategies and potentially reducing the risk of side effects.