Metoprine

• CAT Number: R051880
• CAS Number: 7761-45-7
• Molecular Formula: C11H10Cl2N4
• Molecular Weight: 269.13
• Purity: ≥95%
• Synonyms: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4-?dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3’,4’-dichlorophenyl)-?6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197
• Storage: 2-8°C
• IUPAC Name: 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine
• InChI: InChI=1S/C11H10Cl2N4/c1-5-9(10(14)17-11(15)16-5)6-2-3-7(12)8(13)4-6/h2-4H,1H3,(H4,14,15,16,17)
• InChIKey: VQJHOPSWBGJHQS-UHFFFAOYSA-N
• SMILES: CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl

Metoprine（Cat No.:R051880）is an inhibitor of the enzyme dihydrofolate reductase (DHFR), primarily known for its antiviral properties, particularly against adenoviruses and other RNA viruses. By inhibiting DHFR, metoprine disrupts folate metabolism, which is crucial for nucleotide synthesis and cell division, thereby impeding viral replication. This compound has also shown potential in cancer research due to its ability to interfere with cellular proliferation. Metoprine’s unique mechanism of action makes it a valuable tool in studying viral infections and a potential candidate for developing antiviral therapies and cancer treatments.