For research use only. Not for therapeutic Use.
Metrifonate(Cat No.:I003928), also known as trichlorfon, is an organophosphorus compound that has been used as an insecticide and as an anthelmintic agent. However, it is primarily recognized for its use in the treatment of schistosomiasis, a parasitic disease caused by Schistosoma worms. Metrifonate functions as a reversible acetylcholinesterase inhibitor, leading to the accumulation of acetylcholine at cholinergic synapses and subsequent paralysis of the worms. Due to its ability to selectively target schistosomes, metrifonate has been employed in various regions where schistosomiasis is endemic.
| Catalog Number | I003928 |
| CAS Number | 52-68-6 |
| Synonyms | TRICHLORFON; Chlorophos; Trichlorphon |
| Molecular Formula | C4H8Cl3O4P |
| Purity | ≥95% |
| Solubility | H2O: ≥ 30 mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | 2,2,2-trichloro-1-dimethoxyphosphorylethanol |
| InChI | InChI=1S/C4H8Cl3O4P/c1-10-12(9,11-2)3(8)4(5,6)7/h3,8H,1-2H3 |
| InChIKey | NFACJZMKEDPNKN-UHFFFAOYSA-N |
| SMILES | COP(=O)(C(C(Cl)(Cl)Cl)O)OC |
| Reference | <p style=”/line-height:25px/”> |
