For research use only. Not for therapeutic Use.
Metronidazole Hydrochloride(Cat No.:I032191)is a broad-spectrum antimicrobial agent widely used to treat anaerobic bacterial and protozoal infections. As a prodrug, it is activated within anaerobic cells, disrupting DNA synthesis and leading to cell death. It is effective in managing conditions such as bacterial vaginosis, trichomoniasis, and infections caused by Clostridium difficile. The hydrochloride form enhances its solubility and stability, making it suitable for oral, intravenous, and topical formulations. Metronidazole Hydrochloride is a critical agent in both clinical and research settings, particularly in studies of anaerobic pathogens and antimicrobial resistance.
Catalog Number | I032191 |
CAS Number | 69198-10-3 |
Synonyms | Flagyl; Flagyl ER; Flagyl I.V.; Metronidazole hydrochloride; Metronidazole HCl; SC 32642; SC32642; SC-32642 |
Molecular Formula | C6H10ClN3O3 |
Purity | 98% |
Target | Apoptosis |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | 2-(2-methyl-5-nitroimidazol-1-yl)ethanol;hydrochloride |
InChI | InChI=1S/C6H9N3O3.ClH/c1-5-7-4-6(9(11)12)8(5)2-3-10;/h4,10H,2-3H2,1H3;1H |
InChIKey | FPTPAIQTXYFGJC-UHFFFAOYSA-N |
SMILES | CC1=NC=C(N1CCO)[N+](=O)[O-].Cl |
Reference | 1: Di X, Bai N, Zhang X, Liu B, Ni W, Wang J, Wang K, Liang B, Liu Y, Wang R. A meta-analysis of metronidazole and vancomycin for the treatment of Clostridium difficile infection, stratified by disease severity. Braz J Infect Dis. 2015 Jul-Aug;19(4):339-49. doi: 10.1016/j.bjid.2015.03.006. Epub 2015 May 19. Review. PubMed PMID: 26001980. |