Metronidazole hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: I032191
  • CAS Number: 69198-10-3
  • Molecular Formula: C6H10ClN3O3
  • Molecular Weight: 207.61
  • Purity: 98%
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Metronidazole Hydrochloride(Cat No.:I032191)is a broad-spectrum antimicrobial agent widely used to treat anaerobic bacterial and protozoal infections. As a prodrug, it is activated within anaerobic cells, disrupting DNA synthesis and leading to cell death. It is effective in managing conditions such as bacterial vaginosis, trichomoniasis, and infections caused by Clostridium difficile. The hydrochloride form enhances its solubility and stability, making it suitable for oral, intravenous, and topical formulations. Metronidazole Hydrochloride is a critical agent in both clinical and research settings, particularly in studies of anaerobic pathogens and antimicrobial resistance.


Catalog Number I032191
CAS Number 69198-10-3
Synonyms

Flagyl; Flagyl ER; Flagyl I.V.; Metronidazole hydrochloride; Metronidazole HCl; SC 32642; SC32642; SC-32642

Molecular Formula C6H10ClN3O3
Purity 98%
Target Apoptosis
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-(2-methyl-5-nitroimidazol-1-yl)ethanol;hydrochloride
InChI InChI=1S/C6H9N3O3.ClH/c1-5-7-4-6(9(11)12)8(5)2-3-10;/h4,10H,2-3H2,1H3;1H
InChIKey FPTPAIQTXYFGJC-UHFFFAOYSA-N
SMILES CC1=NC=C(N1CCO)[N+](=O)[O-].Cl
Reference

1: Di X, Bai N, Zhang X, Liu B, Ni W, Wang J, Wang K, Liang B, Liu Y, Wang R. A meta-analysis of metronidazole and vancomycin for the treatment of Clostridium difficile infection, stratified by disease severity. Braz J Infect Dis. 2015 Jul-Aug;19(4):339-49. doi: 10.1016/j.bjid.2015.03.006. Epub 2015 May 19. Review. PubMed PMID: 26001980.
2: Sobel R, Sobel JD. Metronidazole for the treatment of vaginal infections. Expert Opin Pharmacother. 2015 May;16(7):1109-15. doi: 10.1517/14656566.2015.1035255. Review. PubMed PMID: 25887246.
3: Sheehy O, Santos F, Ferreira E, Berard A. The use of metronidazole during pregnancy: a review of evidence. Curr Drug Saf. 2015;10(2):170-9. Review. PubMed PMID: 25986038.
4: Cornely OA, Nathwani D, Ivanescu C, Odufowora-Sita O, Retsa P, Odeyemi IA. Clinical efficacy of fidaxomicin compared with vancomycin and metronidazole in Clostridium difficile infections: a meta-analysis and indirect treatment comparison. J Antimicrob Chemother. 2014 Nov;69(11):2892-900. doi: 10.1093/jac/dku261. Epub 2014 Jul 28. Review. PubMed PMID: 25074856.

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