MFZ 10-7

• CAT Number: I010957
• CAS Number: 1224431-15-5
• Molecular Formula: C15H9FN2
• Molecular Weight: 236.24
• Purity: ≥95%
• Synonyms: 3-fluoro-5-[2-(6-methylpyridin-2-yl)ethynyl]benzonitrile
• IUPAC Name: 3-fluoro-5-[2-(6-methylpyridin-2-yl)ethynyl]benzonitrile;hydrochloride
• InChI: InChI=1S/C15H9FN2.ClH/c1-11-3-2-4-15(18-11)6-5-12-7-13(10-17)9-14(16)8-12;/h2-4,7-9H,1H3;1H
• InChIKey: WRHOKQFFLQKKNL-UHFFFAOYSA-N
• SMILES: CC1=NC(=CC=C1)C#CC2=CC(=CC(=C2)F)C#N.Cl

MFZ 10-7（Cat No.:I010957）is a selective small-molecule inhibitor of the GTPase Rab7, a key protein involved in regulating intracellular vesicle trafficking and endocytic processes. By inhibiting Rab7, MFZ 10-7 disrupts the maturation and transport of endosomes and lysosomes, which plays a critical role in cellular processes like autophagy and protein degradation. Its ability to modulate these pathways has implications for diseases involving dysfunctional vesicle trafficking, such as neurodegenerative disorders. MFZ 10-7 is a valuable tool in cellular biology research for understanding the role of Rab7 in cellular homeostasis and disease mechanisms.