MG-262

For research use only. Not for therapeutic Use.

  • CAT Number: M034274
  • CAS Number: 179324-22-2
  • Molecular Formula: C25H42BN3O6
  • Molecular Weight: 491.43
  • Purity: ≥95%
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MG-262 is a reversible proteasome inhibitor with diverse biological activities[1][2][3].


Catalog Number M034274
CAS Number 179324-22-2
Synonyms

[(1R)-3-methyl-1-[[(2S)-4-methyl-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]pentanoyl]amino]butyl]boronic acid

Molecular Formula C25H42BN3O6
Purity ≥95%
InChI InChI=1S/C25H42BN3O6/c1-16(2)12-20(24(31)29-22(26(33)34)14-18(5)6)27-23(30)21(13-17(3)4)28-25(32)35-15-19-10-8-7-9-11-19/h7-11,16-18,20-22,33-34H,12-15H2,1-6H3,(H,27,30)(H,28,32)(H,29,31)/t20-,21-,22-/m0/s1
InChIKey MWKOOGAFELWOCD-FKBYEOEOSA-N
SMILES B(C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)(O)O
Reference

[1]. Mezquita J, et al. Down-regulation of Flt-1 gene expression by the proteasome inhibitor MG262. J Cell Biochem. 2003 Aug 15;89(6):1138-47.
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