MGH-CP1

• CAT Number: I032227
• CAS Number: 896657-58-2
• Molecular Formula: C20H24N4OS
• Molecular Weight: 368.49
• Purity: 98%
• Synonyms: MGH-CP1; MGHCP1; MGH CP1
• Target: Apoptosis
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: 4°C, away from moisture and light
• IUPAC Name: N-[4-(1-adamantyl)phenyl]-2-(1H-1,2,4-triazol-5-ylsulfanyl)acetamide
• InChI: InChI=1S/C20H24N4OS/c25-18(11-26-19-21-12-22-24-19)23-17-3-1-16(2-4-17)20-8-13-5-14(9-20)7-15(6-13)10-20/h1-4,12-15H,5-11H2,(H,23,25)(H,21,22,24)
• InChIKey: UUKXOVBCMOZQNC-UHFFFAOYSA-N
• SMILES: C1C2CC3CC1CC(C2)(C3)C4=CC=C(C=C4)NC(=O)CSC5=NC=NN5

MGH-CP1（Cat No.:I032227） is a highly potent and selective inhibitor of TEAD (Transcriptional Enhancer Factor Domain) palmitoylation. It specifically targets the palmitoylation process of TEAD proteins, which are key regulators of the Hippo signaling pathway involved in cell proliferation and organ size control. By inhibiting TEAD palmitoylation, MGH-CP1 disrupts the localization and activity of TEAD proteins, leading to downstream effects on target gene expression. This selective inhibition of TEAD palmitoylation provides a valuable tool for studying the Hippo signaling pathway and has potential implications in cancer research and therapeutic development targeting TEAD-regulated pathways.