For research use only. Not for therapeutic Use.
MGL-IN-1（Cat No.:I011967）is a selective inhibitor of monoacylglycerol lipase (MGL), an enzyme involved in the hydrolysis of monoacylglycerols to free fatty acids and glycerol. By inhibiting MGL, this compound modulates endocannabinoid signaling, particularly by increasing levels of 2-arachidonoylglycerol (2-AG), a key endocannabinoid. MGL-IN-1 has shown promise in preclinical studies for its potential therapeutic applications in pain management, inflammation, and neurodegenerative diseases. By enhancing endocannabinoid signaling, it may provide relief in conditions such as chronic pain, anxiety, and disorders related to the central nervous system.
| CAS Number | 1881244-28-5 |
| Synonyms | (3R,4S)-4-(1,3-benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1,2,4-triazole-1-carbonyl)piperidin-4-yl]azetidin-2-one |
| Molecular Formula | C24H22FN5O4 |
| Purity | ≥95% |
| IUPAC Name | (3R,4S)-4-(1,3-benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1,2,4-triazole-1-carbonyl)piperidin-4-yl]azetidin-2-one |
| InChI | InChI=1S/C24H22FN5O4/c25-17-4-1-15(2-5-17)21-22(16-3-6-19-20(11-16)34-14-33-19)30(23(21)31)18-7-9-28(10-8-18)24(32)29-13-26-12-27-29/h1-6,11-13,18,21-22H,7-10,14H2/t21-,22-/m1/s1 |
| InChIKey | XRIROGBLGLPXQI-FGZHOGPDSA-N |
| SMILES | C1CN(CCC1N2[C@@H]([C@H](C2=O)C3=CC=C(C=C3)F)C4=CC5=C(C=C4)OCO5)C(=O)N6C=NC=N6 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
