mGluR3 modulator-1

• CAT Number: I041305
• CAS Number: 374548-18-2
• Molecular Formula: C16H21N3O
• Molecular Weight: 271.36
• Purity: ≥95%
• Synonyms: 1-ethyl-3-morpholin-4-yl-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile
• InChI: InChI=1S/C16H21N3O/c1-2-15-13-6-4-3-5-12(13)14(11-17)16(18-15)19-7-9-20-10-8-19/h2-10H2,1H3
• InChIKey: IPMSLSGLVYALQK-UHFFFAOYSA-N
• SMILES: CCC1=NC(=C(C2=C1CCCC2)C#N)N3CCOCC3

mGluR3 modulator-1 (compound 3) is a mGluR3 modulator, with an EC50 of 1-10 μM in HEK293T-mGluR-Gqi5 Calcium Mobilization Assay[1].

Reference

[1]. Justin Potnick, et al. Modulateurs allostériques positifs de mglur3. Patent. WO2014117919.