For research use only. Not for therapeutic Use.
MHI-148（Cat No.:I042560）is a potent and selective small molecule inhibitor designed to target specific signaling pathways involved in cancer progression. It functions by modulating key proteins associated with cell proliferation, apoptosis, and angiogenesis. This inhibitor has shown promising preclinical results, demonstrating the ability to inhibit tumor growth and metastasis in various cancer models. Additionally, MHI-148 exhibits favorable pharmacokinetic properties, making it a potential candidate for clinical development in cancer therapies. Ongoing studies aim to evaluate its efficacy and safety profile in advanced stages of clinical trials.
| CAS Number | 172971-76-5 |
| Synonyms | 6-[(2E)-2-[(2E)-2-[3-[(E)-2-[1-(5-carboxypentyl)-3,3-dimethylindol-1-ium-2-yl]ethenyl]-2-chlorocyclohex-2-en-1-ylidene]ethylidene]-3,3-dimethylindol-1-yl]hexanoic acid;bromide |
| Molecular Formula | C42H52BrClN2O4 |
| Purity | ≥95% |
| IUPAC Name | 6-[(2E)-2-[(2E)-2-[3-[(E)-2-[1-(5-carboxypentyl)-3,3-dimethylindol-1-ium-2-yl]ethenyl]-2-chlorocyclohex-2-en-1-ylidene]ethylidene]-3,3-dimethylindol-1-yl]hexanoic acid;bromide |
| InChI | InChI=1S/C42H51ClN2O4.BrH/c1-41(2)32-18-9-11-20-34(32)44(28-13-5-7-22-38(46)47)36(41)26-24-30-16-15-17-31(40(30)43)25-27-37-42(3,4)33-19-10-12-21-35(33)45(37)29-14-6-8-23-39(48)49;/h9-12,18-21,24-27H,5-8,13-17,22-23,28-29H2,1-4H3,(H-,46,47,48,49);1H |
| InChIKey | SBSLCJXMLMGYFH-UHFFFAOYSA-N |
| SMILES | CC1(C2=CC=CC=C2[N+](=C1/C=C/C3=C(/C(=C/C=C/4\C(C5=CC=CC=C5N4CCCCCC(=O)O)(C)C)/CCC3)Cl)CCCCCC(=O)O)C.[Br-] |
