MI-773

• CAT Number: I001161
• CAS Number: 1303607-07-9
• Molecular Formula: C29H34Cl2FN3O3
• Molecular Weight: 562.5
• Purity: ≥95%
• Synonyms: MI773;MI 773
• Target: MDM-2/p53; E1/E2/E3 Enzyme
• Solubility: 10 mM in DMSO
• Storage: Store at -20C

MI-773 is an orally available spiro-oxindole HDM2 (human double minute 2) antagonist with potential antineoplastic activity.

Reference

[1]. Preparation of spiro-oxindole compounds as MDM2 antagonists. PCT Int. Appl. (2012), WO 2012065022 A2 


[2]. Biomarkers for MDM2 inhibitors for use in treating leukemia. PCT Int. Appl. (2011), WO 2011127058 A2