Micheliolide

• CAT Number: I004571
• CAS Number: 68370-47-8
• Molecular Formula: C15H20O3
• Molecular Weight: 248.32
• Purity: ≥95%
• Target: NF-κB
• Solubility: 10 mM in DMSO
• Storage: 2-8°C
• IUPAC Name: (3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
• InChI: InChI=1S/C15H20O3/c1-8-4-5-11-9(2)14(16)18-13(11)12-10(8)6-7-15(12,3)17/h11-13,17H,2,4-7H2,1,3H3/t11-,12-,13-,15+/m0/s1
• InChIKey: RDJAFOWISVMOJY-PWNZVWSESA-N
• SMILES: CC1=C2CCC(C2C3C(CC1)C(=C)C(=O)O3)(C)O

Micheliolide（Cat No.:I004571）, is a natural sesquiterpene lactone compound with significant medicinal potential. It is known for its anti-inflammatory, anti-cancer, and anti-microbial properties. Micheliolide exhibits promising activity against various cancer types by inhibiting the growth and proliferation of cancer cells. Additionally, it has been investigated for its potential in treating inflammatory diseases due to its ability to modulate the immune response.

Reference

[1]. Jia QQ, et al. Sesquiterpene lactones and their derivatives inhibit high glucose-induced NF-κB activation and MCP-1 and TGF-β1 expression in rat mesangial cells. Molecules. 2013 Oct 21;18(10):13061-77.