Micronomicin Sulfate

• CAT Number: R028354
• CAS Number: 66803-19-8
• Molecular Formula: C20H43N5O11S
• Molecular Weight: 561.65
• Purity: ≥95%
• Synonyms: O-2-Amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-D-streptamine Sulfate (Salt)
• Target: Antibiotic
• Storage: Store at -20°C
• IUPAC Name: (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;sulfuric acid
• InChI: InChI=1S/C20H41N5O7.H2O4S/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2;1-5(2,3)4/h9-19,24-28H,4-8,21-23H2,1-3H3;(H2,1,2,3,4)/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-;/m0./s1
• InChIKey: MQDGQSCLOYLSEK-SCFBDNQUSA-N
• SMILES: C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CNC)N)N)N)O.OS(=O)(=O)O

Micronomicin sulfate（Cat No.:R028354）is a broad-spectrum aminoglycoside antibiotic derived from Micromonospora species, widely used in pharmaceutical and microbiological research. It inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, demonstrating strong activity against Gram-negative bacteria and select Gram-positive strains. Its stability and efficacy make it a valuable tool for studying bacterial resistance mechanisms and optimizing antibiotic therapies. Micronomicin sulfate is also used in pharmacokinetic studies and the development of novel antimicrobial agents, supporting advancements in infectious disease research and therapeutic strategies.

Reference

Davis, Bernard D. /Mechanism of Bactericidal Action of Aminoglycosides./Microbiological Reviews 51.3 (1987): 341-50.Sarna, Katarzyna, and Agata Blazewicz. /Determination of Gentamicin Sulphate Composition and Related Substances in Pharmaceutical Preparations by LC with Charged Aerosol Detection./ PubMed (2010)Vydrin, A. F. /Component Composition of Gentamicin Sulfate Preparations./ Pharmaceutical Chemistry Journal 37.8 (2003): 448-49. Web. 15 Oct. 2013.Weinstein, Marvin J. /Biological Activity of the Antibiotic Components of the Gentamicin Complex./ Journal of Bacteriology 94.3 (1967): 789-90. Web. 15 Oct. 2013.