microRNA-21-IN-3

For research use only. Not for therapeutic Use.

  • CAT Number: I041151
  • CAS Number: 2766106-83-4
  • Molecular Formula: C16H17N7O
  • Molecular Weight: 323.35
  • Purity: ≥95%
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microRNA-21-IN-3 (compound 45) can specifically bind to the precursor of oncogenic and pro-inflammatory microRNA-21 with medium nanomolar affinity, reduce cancer cell proliferation and miR-21 levels, and can be used in antitumor research[1].


Catalog Number I041151
CAS Number 2766106-83-4
Synonyms

2-[(5-piperazin-1-ylpyridin-2-yl)amino]-3H-pyrido[3,4-d]pyrimidin-4-one

Molecular Formula C16H17N7O
Purity ≥95%
InChI InChI=1S/C16H17N7O/c24-15-12-3-4-18-10-13(12)20-16(22-15)21-14-2-1-11(9-19-14)23-7-5-17-6-8-23/h1-4,9-10,17H,5-8H2,(H2,19,20,21,22,24)
InChIKey DLSJIJCYLWIPFC-UHFFFAOYSA-N
SMILES C1CN(CCN1)C2=CN=C(C=C2)NC3=NC4=C(C=CN=C4)C(=O)N3
Reference

[1]. Matthew D Shortridge, et al. Drug-Like Small Molecules That Inhibit Expression of the Oncogenic MicroRNA-21. ACS Chem Biol. 2023 Feb 17;18(2):237-250. 
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