Mifamurtide

• CAT Number: I005009
• CAS Number: 83461-56-7
• Molecular Formula: C59H109N6O19P
• Molecular Weight: 1237.50
• Purity: ≥95%
• Target: NOD-like Receptor (NLR)
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IUPAC Name: [3-[2-[[(2S)-2-[[(4R)-4-[[(2S)-2-[[(2R)-2-[(2R,3R,4R,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoyl]amino]propanoyl]amino]-5-amino-5-oxopentanoyl]amino]propanoyl]amino]ethoxy-hydroxyphosphoryl]oxy-2-hexadecanoyloxypropyl] hexadecanoate
• InChI: InChI=1S/C59H109N6O19P/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-50(69)79-40-46(83-51(70)34-32-30-28-26-24-22-20-18-16-14-12-10-8-2)41-81-85(77,78)80-38-37-61-56(73)42(3)62-49(68)36-35-47(55(60)72)65-57(74)43(4)63-58(75)44(5)82-54-52(64-45(6)67)59(76)84-48(39-66)53(54)71/h42-44,46-48,52-54,59,66,71,76H,7-41H2,1-6H3,(H2,60,72)(H,61,73)(H,62,68)(H,63,75)(H,64,67)(H,65,74)(H,77,78)/t42-,43-,44+,46?,47+,48+,52+,53?,54+,59+/m0/s1
• InChIKey: JMUHBNWAORSSBD-ZXSMYVEWSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)[C@H](C)NC(=O)CC[C@H](C(=O)N)NC(=O)[C@H](C)NC(=O)[C@@H](C)O[C@@H]1[C@H]([C@@H](O[C@@H](C1O)CO)O)NC(=O)C)OC(=O)CCCCCCCCCCCCCCC

Mifamurtide（Cat No.:I005009）is an immunotherapy drug used in the treatment of osteosarcoma, a rare type of bone cancer. It works by stimulating the immune system to target and destroy cancer cells. Mifamurtide is a liposomal formulation of muramyl tripeptide, a component of bacterial cell walls that activates macrophages, enhancing their ability to recognize and kill tumor cells. It is typically used alongside chemotherapy in patients with high-risk osteosarcoma to improve survival rates. While its use has been shown to increase remission, further studies continue to assess its long-term benefits and safety.