For research use only. Not for therapeutic Use.
Migoprotafib (GDC-1971) (compound 199) is a SHP2 inhibitor[1].
| Catalog Number | I044023 |
| CAS Number | 2377352-49-1 |
| Synonyms | (3R)-1′-[3-(3,4-dihydro-2H-1,5-naphthyridin-1-yl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]spiro[3H-1-benzofuran-2,4′-piperidine]-3-amine |
| Molecular Formula | C25H26N8O |
| Purity | ≥95% |
| InChI | InChI=1S/C25H26N8O/c26-22-16-5-1-2-8-19(16)34-25(22)9-13-32(14-10-25)20-15-28-21-23(29-20)30-31-24(21)33-12-4-6-17-18(33)7-3-11-27-17/h1-3,5,7-8,11,15,22H,4,6,9-10,12-14,26H2,(H,29,30,31)/t22-/m1/s1 |
| InChIKey | RGCGBFIARQENML-JOCHJYFZSA-N |
| SMILES | C1CC2=C(C=CC=N2)N(C1)C3=NNC4=NC(=CN=C43)N5CCC6(CC5)C(C7=CC=CC=C7O6)N |
| Reference | [1]. Alexander M, et al. Shp2 phosphatase inhibitors and methods of use thereof. Patent WO2019183367A1. |
