For research use only. Not for therapeutic Use.
Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of ＜5 μM[1].
| Catalog Number | I032282 |
| CAS Number | 859217-52-0 |
| Synonyms | 1-(cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine |
| Molecular Formula | C24H38N2 |
| Purity | ≥95% |
| InChI | InChI=1S/C24H38N2/c1-23(2)15-20(16-24(3,4)18-23)21-7-5-6-8-22(21)26-13-11-25(12-14-26)17-19-9-10-19/h5-8,19-20H,9-18H2,1-4H3 |
| InChIKey | PGWIKFFLIJECAM-UHFFFAOYSA-N |
| SMILES | CC1(CC(CC(C1)(C)C)C2=CC=CC=C2N3CCN(CC3)CC4CC4)C |
| Reference | [1]. Kotake, Makoto; Yoneda, Naoki; Osada, Katsunobu.Preparation of various crystal forms and salts of 1-cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine for treating or preventing various inflammatory diseases and autoimmune diseases.WO |
