Mimosine hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: I032303
  • CAS Number: 62766-26-1
  • Molecular Formula: C8H11ClN2O4
  • Molecular Weight: 234.64
  • Purity: 98%
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Mimosine hydrochloride(Cat No.:I032303)is a plant-derived compound isolated from Mimosa species, particularly Mimosa pudica. It is an amino acid analog that acts as a potent inhibitor of DNA synthesis by chelating iron and disrupting ribonucleotide reductase activity. Due to its ability to interfere with cell division, mimosine hydrochloride has been studied for its potential as an anticancer agent. It also exhibits phytotoxic properties, making it useful in plant research for studying cell cycle regulation and growth inhibition. However, its toxic effects limit its use, and further studies are needed to explore its therapeutic potential and safety.


Catalog Number I032303
CAS Number 62766-26-1
Synonyms

Mimosine hydrochloride; Mimosine HCl

Molecular Formula C8H11ClN2O4
Purity 98%
Solubility To be determined
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name (2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid;hydrochloride
InChI InChI=1S/C8H10N2O4.ClH/c9-5(8(13)14)3-10-2-1-6(11)7(12)4-10;/h1-2,4-5,12H,3,9H2,(H,13,14);1H/t5-;/m0./s1
InChIKey NKMVNJHZWMQDIP-JEDNCBNOSA-N
SMILES C1=CN(C=C(C1=O)O)C[C@@H](C(=O)O)N.Cl
Reference

1: Palumbo A, d’Ischia M, Misuraca G, De Martino L, Prota G. A new dopachrome-rearranging enzyme from the ejected ink of the cuttlefish Sepia officinalis. Biochem J. 1994 May 1;299 ( Pt 3):839-44. PubMed PMID: 8192674; PubMed Central PMCID: PMC1138097.
2: Aroca P, Solano F, Garcia-Borrón JC, Lozano JA. Specificity of dopachrome tautomerase and inhibition by carboxylated indoles. Considerations on the enzyme active site. Biochem J. 1991 Jul 15;277 ( Pt 2):393-7. PubMed PMID: 1859367; PubMed Central PMCID: PMC1151246.

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