For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.</p>
| Catalog Number | I002880 |
| CAS Number | 25905-77-5 |
| Molecular Formula | C17H22N4O |
| Purity | ≥95% |
| Target | Monoamine Oxidase |
| Solubility | DMSO: ≥ 35 mg/mL |
| Storage | Store at -20°C |
| Reference | </br>1:Double-blind comparative study of the antidepressant, unwanted and cardiac effects of minaprine and amitriptyline. Edwards JG, Dinan TG, Waller DG, Greentree SG.Br J Clin Pharmacol. 1996 Oct;42(4):491-8. PMID: 8904622 Free PMC Article</br>2:[Evaluation by poison control centers of minaprine from the modification of tablet dosages]. Jouglard J, Perringue C, Goujard J, Servetti A, David JM.Therapie. 1996 Sep-Oct;51(5):582-5. French. PMID: 9138401 </br>3:[Randomized double-blind comparative study of minaprine (200mg/j) and of placebo on memory loss]. Allain H, Belliard S, Lieury A, Menard G, Patat A, Le Coz F, Gandon JM.Therapie. 1996 Mar-Apr;51(2):155-62. French. PMID: 8763050 </br>4:A comparison of the behavioral effects of minaprine, amphetamine and stress. Cabib S, Zocchi A, Puglisi-Allegra S.Psychopharmacology (Berl). 1995 Sep;121(1):73-80. PMID: 8539343 </br>5:Prevention by minaprine of ischemic neuronal damage and memory impairment in Mongolian gerbils. Piao Y, Mineshita S, Kuroiwa T, Koike Y.Nihon Shinkei Seishin Yakurigaku Zasshi. 1995 Apr;15(2):157-63. PMID: 7796320 </br>6:Multicentric double-blind study comparing efficacy and safety of minaprine and imipramine in dysthymic disorders. Salzmann E, Robin JL.Neuropsychobiology. 1995;31(2):68-75. PMID: 7760988 </br>7:Minaprine, but not oxiracetam, prevents desipramine-induced impairment of avoidance learning in mice. Sansone M, Battaglia M, Vetulani J.Pol J Pharmacol. 1995 Jan-Feb;47(1):69-73. PMID: 7550552 </br>8:Effects of subchronic minaprine on dopamine release in the ventral striatum and on immobility in the forced swimming test. Imperato A, Obinu MC, Cabib S, Cestari V, Puglisi-Allegra S.Neurosci Lett. 1994 Jan 17;166(1):69-72. PMID: 8190361 </br>9:Involvement of protein kinase C activation in regulation of acetylcholine release from rat hippocampal slices by minaprine. Chaki S, Muramatsu M, Otomo S.Neurochem Int. 1994 Jan;24(1):37-41. PMID: 8130734 </br>10:Post-training minaprine enhances memory storage in mice: involvement of D1 and D2 dopamine receptors. Puglisi-Allegra S, Cabib S, Cestari V, Castellano C.Psychopharmacology (Berl). 1994 Jan;113(3-4):476-80. PMID: 7862862 |
