For research use only. Not for therapeutic Use.
MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington’s disease[1].
| Catalog Number | I043426 |
| CAS Number | 129544-85-0 |
| Synonyms | 3-benzylsulfanyl-5-(phenoxymethyl)-4-phenyl-1,2,4-triazole |
| Molecular Formula | C22H19N3OS |
| Purity | ≥95% |
| InChI | InChI=1S/C22H19N3OS/c1-4-10-18(11-5-1)17-27-22-24-23-21(16-26-20-14-8-3-9-15-20)25(22)19-12-6-2-7-13-19/h1-15H,16-17H2 |
| InChIKey | SSZGXGUFAAHHAF-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CSC2=NN=C(N2C3=CC=CC=C3)COC4=CC=CC=C4 |
| Reference | [1]. Quinti L, et al. SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington’s Disease Models. Cell Chem Biol. 2016 Jul 21;23(7):849-861. |
