Minocycline-d7 (Major)

• CAT Number: R034277
• CAS Number: NA
• Molecular Formula: C₂₃H₂₀D₇N₃O₇
• Molecular Weight: 464.52
• Purity: ≥95%
• Synonyms: (4S,4aS,5aR,12aS)-4-(Dimethylamino)-7-[di(methyl-d3)amino]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide-d7
• Storage: -20°C
• IUPAC Name: (4S,4aS,5aR,12aR)-7-[bis(trideuteriomethyl)amino]-4-deuterio-4-(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydrotetracene-2-carboxamide
• InChI: InChI=1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1/i1D3,2D3,17D
• InChIKey: FFTVPQUHLQBXQZ-OHETUYDCSA-N
• SMILES: [2H][C@@]1([C@@H]2C[C@@H]3CC4=C(C=CC(=C4C(=C3C(=O)[C@@]2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C([2H])([2H])[2H])C([2H])([2H])[2H])N(C)C

Minocycline-d7 is a deuterated analog of Minocycline, a broad-spectrum tetracycline antibiotic used to treat a range of bacterial infections, including acne and respiratory infections. The deuterium labeling in Minocycline-d7 enhances the precision of pharmacokinetic and metabolic studies by allowing accurate tracking and quantification in biological systems. This compound is valuable in pharmaceutical research for understanding the drug’s metabolic pathways, bioavailability, and excretion, which helps in optimizing therapeutic efficacy and safety. In organic chemistry, Minocycline-d7 is used to study reaction mechanisms and develop new synthetic methodologies, contributing to advancements in antibiotic research and drug development.