Mirabegron impurity-1

• CAT Number: R024655
• CAS Number: 391901-45-4
• Molecular Formula: C16H20N2O
• Molecular Weight: 256.34
• Purity: ≥95%
• Synonyms: (1R)-2-[2-(4-aminophenyl)ethylamino]-1-phenylethanol
• InChI: InChI=1S/C16H20N2O/c17-15-8-6-13(7-9-15)10-11-18-12-16(19)14-4-2-1-3-5-14/h1-9,16,18-19H,10-12,17H2/t16-/m0/s1
• InChIKey: TUAHDMSPHZSMQN-INIZCTEOSA-N
• SMILES: C1=CC=C(C=C1)C(CNCCC2=CC=C(C=C2)N)O

Mirabegron impurity-1 is a potent and selective
β3- adrenergic receptor agonist. Mirabegron impurity-1
has the activity of inhibiting metabolism. Mirabegron impurity-1 can be used in
the study of the treatment of bladder impurity [1].

Reference

[1]. Takusagawa S, et al. Identification of human cytochrome P450 isoforms and esterases involved in the metabolism of mirabegron, a potent and selective β3-adrenoceptor agonist. Xenobiotica. 2012 Oct;42(10):957-67.
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