Misonidazole

• CAT Number: R028891
• CAS Number: 13551-87-6
• Molecular Formula: C7H11N3O4
• Molecular Weight: 201.18
• Purity: ≥95%
• Synonyms: α-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol; α-(Methoxymethyl)-2-nitroimidazole-1-ethanol; 1-(2-Hydroxy-3-methoxypropyl)-2-nitroimidazole; 1-(2-Nitro-1-imidazolyl)-3-methoxy-2-propanol; 2-Nitro-1H-imidazole-1-(3-methoxy-2-propanol); NSC 261037
• Target: Bacterial
• Storage: -20°C
• IUPAC Name: 1-methoxy-3-(2-nitroimidazol-1-yl)propan-2-ol
• InChI: InChI=1S/C7H11N3O4/c1-14-5-6(11)4-9-3-2-8-7(9)10(12)13/h2-3,6,11H,4-5H2,1H3
• InChIKey: OBBCSXFCDPPXOL-UHFFFAOYSA-N
• SMILES: COCC(CN1C=CN=C1[N+](=O)[O-])O

Misonidazole（Cat No.:R028891）is a radiosensitizer used in cancer therapy to enhance the effectiveness of radiotherapy, particularly in hypoxic tumor cells that are less responsive to radiation. It selectively targets low-oxygen regions within tumors, where it becomes activated to produce cytotoxic free radicals, leading to DNA damage and cell death. Misonidazole is crucial in research focused on improving radiotherapy outcomes, understanding tumor hypoxia, and developing targeted cancer treatments. Its role in enhancing radiation sensitivity makes it a valuable compound for advancing therapies against resistant tumor types and optimizing cancer treatment protocols.