Mizolastine dihydrochloride

• CAT Number: I000292
• CAS Number: 1056596-82-7
• Molecular Formula: C24H27Cl2FN6O
• Molecular Weight: 505.42
• Purity: ≥95%
• Synonyms: 2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4-ol dihydrochloride
• Target: Neuronal Signaling
• Solubility: 10 mM in DMSO
• Storage: Store at -20C
• IUPAC Name: 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one;dihydrochloride
• InChI: InChI=1S/C24H25FN6O.2ClH/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17;;/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32);2*1H
• InChIKey: VSBSKWNPRUHSSV-UHFFFAOYSA-N
• SMILES: CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5.Cl.Cl

Mizolastine dihydrochloride（Cat No.:I000292）is a second-generation antihistamine commonly used to treat allergic conditions, including hay fever, allergic rhinitis, and urticaria (hives). It works by selectively blocking histamine H1 receptors, which are responsible for allergic symptoms like itching, sneezing, and swelling. Mizolastine has a low sedative effect compared to first-generation antihistamines, making it preferable for long-term use. It is also less likely to cross the blood-brain barrier, reducing the risk of drowsiness. Mizolastine dihydrochloride is typically well-tolerated and is used in both acute and chronic management of allergic reactions.