MK-1903

• CAT Number: I008050
• CAS Number: 1268882-43-4
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.16
• Purity: ≥95%
• Synonyms: (2R,4R)-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxylic acid
• InChI: InChI=1S/C8H8N2O2/c11-8(12)7-5-2-3-1-4(3)6(5)9-10-7/h3-4H,1-2H2,(H,9,10)(H,11,12)/t3-,4-/m1/s1
• InChIKey: CUTZNERBKDMLAP-QWWZWVQMSA-N
• SMILES: C1C2C1C3=C(C2)C(=NN3)C(=O)O

MK-1903 is a potent and selective hydroxycarboxylic acid receptor 2 (HCA2, GPR109A) full agonist[1].

Reference

[1]. Boatman PD, et al. (1aR,5aR)1a,3,5,5a-Tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid (MK-1903): a potent GPR109a agonist that lowers free fatty acids in humans. J Med Chem. 2012 Apr 26;55(8):3644-66.
 [Content Brief]