MK 386

• CAT Number: I011318
• CAS Number: 158493-17-5
• Molecular Formula: C28H49NO
• Molecular Weight: 415.706
• Purity: ≥95%
• Synonyms: (4aR,4bS,6aR,7R,9aS,9bS,10S,11aR)-7-[(1R)-1,5-Dimethylhexyl]hexadecahydro-1,4a,6a,10-tetramethyl-2H-indeno[5,4-f]quinolin-2-one
• Solubility: Soluble to 100 mM in DMSO
• Storage: Store at -20C
• IUPAC Name: (1R,3aS,3bS,4S,5aR,9aR,9bS,11aR)-4,6,9a,11a-tetramethyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-7-one
• InChI: InChI=1S/C28H49NO/c1-18(2)9-8-10-19(3)21-11-12-22-26-20(4)17-24-28(6,16-14-25(30)29(24)7)23(26)13-15-27(21,22)5/h18-24,26H,8-17H2,1-7H3/t19-,20+,21-,22+,23+,24-,26+,27-,28-/m1/s1
• InChIKey: XUTZDXHKQDPUMA-MVJJLJOTSA-N
• SMILES: CC1CC2C(CCC(=O)N2C)(C3C1C4CCC(C4(CC3)C)C(C)CCCC(C)C)C

MK 386 (Cat.No:I011318) is a potent and selective non-steroidal antagonist of the progesterone receptor. It acts by inhibiting the binding of progesterone to its receptor, thereby interfering with progesterone-mediated signaling pathways. MK 386 has been investigated for its potential therapeutic applications in hormone-related conditions such as breast cancer and endometriosis.