MK-4101

• CAT Number: I005555
• CAS Number: 935273-79-3
• Molecular Formula: C₂₄H₂₄F₅N₅O
• Molecular Weight: 493.48
• Purity: ≥95%
• Synonyms: MK4101;MK 4101
• Target: Apoptosis
• Solubility: DMSO: 10 mM
• Storage: Store at -20°C
• IUPAC Name: 5-(3,3-difluorocyclobutyl)-3-[4-[4-methyl-5-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-3-yl]-1-bicyclo[2.2.2]octanyl]-1,2,4-oxadiazole
• InChI: InChI=1S/C24H24F5N5O/c1-34-17(15-4-2-3-5-16(15)24(27,28)29)31-32-20(34)22-9-6-21(7-10-22,8-11-22)19-30-18(35-33-19)14-12-23(25,26)13-14/h2-5,14H,6-13H2,1H3
• InChIKey: HKJOIWLYDJCTQR-UHFFFAOYSA-N
• SMILES: CN1C(=NN=C1C23CCC(CC2)(CC3)C4=NOC(=N4)C5CC(C5)(F)F)C6=CC=CC=C6C(F)(F)F

MK-4101（Cat No.:I005555）is a selective small molecule inhibitor of the enzyme phosphodiesterase 4 (PDE4), which plays a key role in regulating cyclic AMP (cAMP) levels within cells. By inhibiting PDE4, MK-4101 increases cAMP levels, leading to anti-inflammatory effects. This makes it a promising candidate for treating conditions associated with inflammation, such as chronic obstructive pulmonary disease (COPD), asthma, and psoriasis. Additionally, MK-4101 may have applications in neurological disorders, where PDE4 inhibition has been linked to potential cognitive and mood-enhancing effects. Further clinical studies are needed to evaluate its safety and efficacy.