For research use only. Not for therapeutic Use.
MK8722 (CAT: I019897) is a potent and systemic pan-AMPK (adenosine monophosphate-activated protein kinase) activator. AMPK is an enzyme that plays a crucial role in cellular energy homeostasis and metabolism. Activation of AMPK can promote various metabolic processes, such as glucose uptake, fatty acid oxidation, and mitochondrial biogenesis, while inhibiting energy-consuming pathways. MK8722 is designed to activate AMPK in a broad range of tissues, thereby enhancing energy production and utilization. This pan-AMPK activation has the potential to be beneficial in various metabolic disorders, including type 2 diabetes, obesity, and cardiovascular diseases.
| Catalog Number | I019897 |
| CAS Number | 1394371-71-1 |
| Molecular Formula | C₂₄H₂₀ClN₃O₄ |
| Purity | ≥95% |
| Reference | [1]. Myers RW, et al. Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiachypertrophy. Science. 2017 Aug 4;357(6350):507-511. |
