ML 00253764 hydrochloride

• CAT Number: I011656
• CAS Number: 681847-92-7
• Molecular Formula: C18H19BrClFN2O
• Molecular Weight: 413.72
• Purity: ≥95%
• Synonyms: 2-(2-(5-bromo-2-methoxyphenethyl)-3-fluorophenyl)-4,5-dihydro-1H-imidazole hydrochloride
• Target: Melanocortin (MC) Receptors
• Solubility: Soluble in DMSO > 10 mM
• Storage: Store at +4C
• IUPAC Name: 2-[2-[2-(5-bromo-2-methoxyphenyl)ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole
• InChI: InChI=1S/C18H18BrFN2O/c1-23-17-8-6-13(19)11-12(17)5-7-14-15(3-2-4-16(14)20)18-21-9-10-22-18/h2-4,6,8,11H,5,7,9-10H2,1H3,(H,21,22)
• InChIKey: WCPPZGPJRHLSKP-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=C1)Br)CCC2=C(C=CC=C2F)C3=NCCN3

ML 00253764 hydrochloride (Cat No.:I011656) is a potent and selective inhibitor of the Rho-associated protein kinase (ROCK) that plays a key role in regulating various cellular processes, including cell contraction, motility, proliferation, and apoptosis. ML 00253764 hydrochloride works by inhibiting the activity of the ROCK enzymes, thereby reducing the phosphorylation of downstream targets and disrupting the cytoskeleton organization. The inhibition of ROCK by ML 00253764 hydrochloride has been shown to have therapeutic potential for the treatment of various diseases, including cardiovascular diseases, neurological disorders, and cancer.