For research use only. Not for therapeutic Use.
ML-SA5（Cat No.:I032447）is a small molecule compound that acts as a potent inhibitor of the protein MLKL (Mixed Lineage Kinase Domain-Like), a key player in the process of necroptosis, a form of programmed cell death. By inhibiting MLKL, ML-SA5 suppresses necroptosis, which is implicated in various diseases, including neurodegenerative disorders, inflammatory conditions, and ischemic injury. Research has shown that ML-SA5 has potential therapeutic applications, particularly in preventing excessive cell death and tissue damage associated with these diseases. Its development could offer new treatment strategies for conditions involving uncontrolled cell death.
| Catalog Number | I032447 |
| CAS Number | 2418670-70-7 |
| Synonyms | 1-N-(3-chloro-2-piperidin-1-ylphenyl)-4-N,4-N-dimethylbenzene-1,4-disulfonamide |
| Molecular Formula | C19H24ClN3O4S2 |
| Purity | ≥95% |
| IUPAC Name | 1-N-(3-chloro-2-piperidin-1-ylphenyl)-4-N,4-N-dimethylbenzene-1,4-disulfonamide |
| InChI | InChI=1S/C19H24ClN3O4S2/c1-22(2)29(26,27)16-11-9-15(10-12-16)28(24,25)21-18-8-6-7-17(20)19(18)23-13-4-3-5-14-23/h6-12,21H,3-5,13-14H2,1-2H3 |
| InChIKey | YPPWKTIVYUTTEH-UHFFFAOYSA-N |
| SMILES | CN(C)S(=O)(=O)C1=CC=C(C=C1)S(=O)(=O)NC2=C(C(=CC=C2)Cl)N3CCCCC3 |
