For research use only. Not for therapeutic Use.
ML261（Cat No.:R061162）is a thienopyrrole-5-carboxamide derivative that inhibits hepatic lipid droplet formation, with an IC₅₀ value of 69.7 nM. It has been investigated for its potential in treating non-alcoholic fatty liver disease (NAFLD) and inflammation. In vitro studies demonstrate that ML261 effectively reduces lipid accumulation in murine AML-12 hepatocytes but does not significantly affect human Huh7 hepatocellular carcinoma cells or primary human hepatocytes. The compound has a molecular formula of C₂₀H₂₃ClN₂O₃S and a molecular weight of 406.93 g/mol. ML261 is soluble in DMSO at concentrations up to 5 mg/mL and should be stored at 2-8 °C to maintain stability.
| CAS Number | 902523-58-4 |
| Synonyms | 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methylthieno[3,2-b]pyrrole-5-carboxamide |
| Molecular Formula | C20H23ClN2O3S |
| Purity | ≥95% |
| IUPAC Name | 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methylthieno[3,2-b]pyrrole-5-carboxamide |
| InChI | InChI=1S/C20H23ClN2O3S/c1-4-25-16-7-6-13(10-17(16)26-5-2)8-9-22-20(24)15-11-18-14(23(15)3)12-19(21)27-18/h6-7,10-12H,4-5,8-9H2,1-3H3,(H,22,24) |
| InChIKey | DGNXYXASQJMULD-UHFFFAOYSA-N |
| SMILES | CCOC1=C(C=C(C=C1)CCNC(=O)C2=CC3=C(N2C)C=C(S3)Cl)OCC |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
