For research use only. Not for therapeutic Use.
ML261 is a hepatic lipid droplets formation inhibitor with an IC50 value of 69.7 nM. ML261 can be used for the research of non-alcoholic fatty liver disease (NAFLD) and inflammation[1].
ML261 (1 nM-10 μM; 24 h) affects hepatic lipid droplets formation in murine AML-12 cells[1].
| Catalog Number | R061162 |
| CAS Number | 902523-58-4 |
| Synonyms | 2-chloro-N-[2-(3,4-diethoxyphenyl)ethyl]-4-methylthieno[3,2-b]pyrrole-5-carboxamide |
| Molecular Formula | C20H23ClN2O3S |
| Purity | ≥95% |
| InChI | InChI=1S/C20H23ClN2O3S/c1-4-25-16-7-6-13(10-17(16)26-5-2)8-9-22-20(24)15-11-18-14(23(15)3)12-19(21)27-18/h6-7,10-12H,4-5,8-9H2,1-3H3,(H,22,24) |
| InChIKey | DGNXYXASQJMULD-UHFFFAOYSA-N |
| SMILES | CCOC1=C(C=C(C=C1)CCNC(=O)C2=CC3=C(N2C)C=C(S3)Cl)OCC |
| Reference | [1]. Zou J, et al. Potent inhibitors of lipid droplet formation. 2014. |
