ML264

• CAT Number: I001958
• CAS Number: 1550008-55-3
• Molecular Formula: C17H21ClN2O4S
• Molecular Weight: 384.90
• Purity: ≥95%
• Synonyms: (2E)-3-(3-chlorophenyl)-N-[2-[methyl(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)amino]-2-oxoethyl]-2-propenamide
• Target: KLF
• Solubility: Soluble in DMSO, not in water
• Storage: Store at -20°C
• IUPAC Name: (E)-3-(3-chlorophenyl)-N-[2-[(1,1-dioxothian-4-yl)-methylamino]-2-oxoethyl]prop-2-enamide
• InChI: InChI=1S/C17H21ClN2O4S/c1-20(15-7-9-25(23,24)10-8-15)17(22)12-19-16(21)6-5-13-3-2-4-14(18)11-13/h2-6,11,15H,7-10,12H2,1H3,(H,19,21)/b6-5+
• InChIKey: AJCDZIDKYKCOMZ-AATRIKPKSA-N
• SMILES: CN(C1CCS(=O)(=O)CC1)C(=O)CNC(=O)/C=C/C2=CC(=CC=C2)Cl

ML264（Cat No.:I001958）is a selective, small-molecule inhibitor of the protein kinase S6K1 (ribosomal protein S6 kinase 1), which is part of the mTOR (mechanistic target of rapamycin) signaling pathway. S6K1 plays a critical role in regulating cell growth, protein synthesis, and metabolism in response to nutrients and growth factors. By inhibiting S6K1, ML264 can suppress cellular processes that contribute to cancer progression, metabolic disorders, and neurodegenerative diseases. Preclinical studies suggest that ML264 has potential therapeutic applications in oncology and other diseases characterized by dysregulated cell growth and metabolism.