ML266

• CAT Number: I012414
• CAS Number: 1462267-08-8
• Molecular Formula: C24H22BrN3O4
• Molecular Weight: 496.35
• Purity: ≥95%
• Synonyms: 2-[2-(4-bromoanilino)-2-oxoethoxy]-N-[2-(N-methylanilino)-2-oxoethyl]benzamide
• InChI: InChI=1S/C24H22BrN3O4/c1-28(19-7-3-2-4-8-19)23(30)15-26-24(31)20-9-5-6-10-21(20)32-16-22(29)27-18-13-11-17(25)12-14-18/h2-14H,15-16H2,1H3,(H,26,31)(H,27,29)
• InChIKey: VAPWBKACLHRZBZ-UHFFFAOYSA-N
• SMILES: CN(C1=CC=CC=C1)C(=O)CNC(=O)C2=CC=CC=C2OCC(=O)NC3=CC=C(C=C3)Br

ML266（Cat No.:I012414）is a selective small molecule inhibitor that targets the protein C11ORF58, a key regulator in the autophagy pathway. By inhibiting C11ORF58, ML266 disrupts the process of autophagic flux, which plays a critical role in cellular homeostasis and survival. This compound has shown promise in preclinical models as a potential therapeutic agent for cancer, neurodegenerative diseases, and other conditions where autophagy regulation is disrupted. ML266’s ability to modulate autophagy may offer a novel approach for treating diseases associated with impaired cellular degradation and recycling.