ML345（Cat No.:R028715）is a selective small molecule inhibitor that targets the protein PIKfyve, an enzyme involved in the regulation of phosphoinositide metabolism and cellular signaling. PIKfyve is critical for the formation of lipid signals that regulate cellular processes such as endocytosis, autophagy, and membrane trafficking. By inhibiting PIKfyve, ML345 disrupts these processes, which has potential therapeutic implications for diseases such as cancer, neurodegenerative disorders, and infections. Preclinical studies suggest that ML345 may offer a novel approach to modulate cellular trafficking and autophagy for therapeutic benefit.