For research use only. Not for therapeutic Use.
MLS-573151 (Cat No.:I011544) is a specific inhibitor of the GTPase Cdc42, with an EC50 value of 2 μM. It selectively targets Cdc42 and does not inhibit other members of the GTPase family, including Rab2, Rab7, H-Ras, Rac1, Rac2, and RhoA wild type. Its mode of action involves preventing the binding of GTP to Cdc42. MLS-573151 shows potential as a valuable tool in studying the functions and signaling pathways involving Cdc42, a key regulator of cellular processes such as cell migration, proliferation, and cytoskeletal organization.
| Catalog Number | I011544 |
| CAS Number | 10179-57-4 |
| Synonyms | 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-benzenesulfonamide |
| Molecular Formula | C21H19N3O2S |
| Purity | ≥95% |
| Target | MAPK/ERK Pathway |
| Solubility | Soluble in DMSO |
| Storage | Store at RT |
| IUPAC Name | 4-(3,5-diphenyl-3,4-dihydropyrazol-2-yl)benzenesulfonamide |
| InChI | InChI=1S/C21H19N3O2S/c22-27(25,26)19-13-11-18(12-14-19)24-21(17-9-5-2-6-10-17)15-20(23-24)16-7-3-1-4-8-16/h1-14,21H,15H2,(H2,22,25,26) |
| InChIKey | OPPCVEVPKHRJNY-UHFFFAOYSA-N |
| SMILES | C1C(N(N=C1C2=CC=CC=C2)C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4 |
