MMAE-d8

• CAT Number: S000001
• CAS Number: 2070009-72-0
• Molecular Formula: C39H59D8N5O7
• Molecular Weight: 726.03
• Purity: ≥95%
• Target: Cytoskeleton
• IUPAC Name: (2S)-2,3,4,4,4-pentadeuterio-N-[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]-3-(trideuteriomethyl)butanamide
• InChI: InChI=1S/C39H67N5O7/c1-13-25(6)34(43(10)39(49)33(24(4)5)42-38(48)32(40-9)23(2)3)30(50-11)22-31(45)44-21-17-20-29(44)36(51-12)26(7)37(47)41-27(8)35(46)28-18-15-14-16-19-28/h14-16,18-19,23-27,29-30,32-36,40,46H,13,17,20-22H2,1-12H3,(H,41,47)(H,42,48)/t25-,26+,27+,29-,30+,32-,33-,34-,35+,36+/m0/s1/i4D3,5D3,24D,33D
• InChIKey: DASWEROEPLKSEI-CMHCZSPYSA-N
• SMILES: [2H][C@@](C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])NC(=O)[C@H](C(C)C)NC

MMAE-d8 is a high-purity deuterated compound essential for advanced pharmaceutical and biochemical research. This isotopically labeled version of Monomethyl Auristatin E (MMAE) is pivotal for studies involving antibody-drug conjugates (ADCs), cytotoxicity assays, and cancer therapeutics. Featuring eight deuterium atoms, it ensures precise and reliable analytical results. Its advanced formulation provides enhanced stability and consistency, making it suitable for various experimental setups. Ideal for oncology research and drug development, MMAE-d8 integrates seamlessly into existing protocols, offering a robust and cost-effective solution for high-precision scientific investigations.