For research use only. Not for therapeutic Use.
MMAF-OtBu (Example 2) is a modified MMAF (HY-15579 ). MMAF-OtBu can be used for synthesis of ADCs[1].
Catalog Number | I040074 |
CAS Number | 745017-95-2 |
Synonyms | tert-butyl (2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoate |
Molecular Formula | C43H73N5O8 |
Purity | ≥95% |
InChI | InChI=1S/C43H73N5O8/c1-15-28(6)37(47(12)41(52)36(27(4)5)46-40(51)35(44-11)26(2)3)33(54-13)25-34(49)48-23-19-22-32(48)38(55-14)29(7)39(50)45-31(42(53)56-43(8,9)10)24-30-20-17-16-18-21-30/h16-18,20-21,26-29,31-33,35-38,44H,15,19,22-25H2,1-14H3,(H,45,50)(H,46,51)/t28-,29+,31-,32-,33+,35-,36-,37-,38+/m0/s1 |
InChIKey | HMBFRLXQUOOKLK-VFSYNPLYSA-N |
SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)OC(C)(C)C)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC |
Reference | [1]. Svetlana O, et al. DoroninaMonomethylvaline compounds capable of conjugation to ligands. Patent. WO2005081711. |