MMG-11

• CAT Number: I019481
• CAS Number: 313254-94-3
• Molecular Formula: C₁₅H₁₄O₇
• Molecular Weight: 306.27
• Purity: ≥95%
• Target: Toll-like Receptor (TLR)
• IUPAC Name: ethyl 5-[2-oxo-2-(2,3,4-trihydroxyphenyl)ethyl]furan-2-carboxylate
• InChI: InChI=1S/C15H14O7/c1-2-21-15(20)12-6-3-8(22-12)7-11(17)9-4-5-10(16)14(19)13(9)18/h3-6,16,18-19H,2,7H2,1H3
• InChIKey: IIDUJWIVMGALOG-UHFFFAOYSA-N
• SMILES: CCOC(=O)C1=CC=C(O1)CC(=O)C2=C(C(=C(C=C2)O)O)O

MMG-11(CAT: I019481) is a selective inhibitor of heat shock protein 90 (Hsp90), a molecular chaperone essential for the stability and function of various client proteins involved in cellular signaling, proliferation, and survival. By binding to the ATP-binding domain of Hsp90, MMG-11 disrupts its chaperone activity, leading to the degradation of client proteins and the inhibition of oncogenic pathways. This mechanism makes MMG-11 a valuable tool in cancer research, particularly for studying the role of Hsp90 in tumor progression, metastasis, and drug resistance. MMG-11 holds potential for the development of targeted therapies against Hsp90-dependent cancers.