For research use only. Not for therapeutic Use.
MN58b (Cat.No:I017992) is a small molecule inhibitor that has shown promising anticancer activity in preclinical studies. It targets and inhibits the activity of several enzymes involved in cancer cell growth and survival pathways, leading to cell cycle arrest and apoptosis. MN58b is being investigated for its potential therapeutic use in the treatment of various types of cancers.
Catalog Number | I017992 |
CAS Number | 203192-01-2 |
Molecular Formula | C₃₂H₄₀Br₂N₄ |
Purity | ≥95% |
Target | Apoptosis |
Reference | [1]. Mazarico JM, et al. Choline Kinase Alpha (CHKα) as a Therapeutic Target in Pancreatic Ductal Adenocarcinoma: Expression, Predictive Value, and Sensitivity to Inhibitors. Mol Cancer Ther. 2016 Feb;15(2):323-33.<br>[2]. Al-Saffar NM, et al. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models. Cancer Res. 2006 Jan 1;66(1):427-34. |