Mn(II)-DO3A sodium

• CAT Number: I040020
• CAS Number: 120066-53-7
• Molecular Formula: C14H23MnN4NaO6
• Molecular Weight: 421.28
• Purity: ≥95%
• Synonyms: sodium;2-[4,7-bis(carboxylatomethyl)-1,4,7-triaza-10-azanidacyclododec-1-yl]acetate;manganese(2+)
• InChI: InChI=1S/C14H25N4O6.Mn.Na/c19-12(20)9-16-3-1-15-2-4-17(10-13(21)22)6-8-18(7-5-16)11-14(23)24;;/h1-11H2,(H,19,20)(H,21,22)(H,23,24);;/q-1;+2;+1/p-3
• InChIKey: OVRMTVHRWWZGAL-UHFFFAOYSA-K
• SMILES: C1CN(CCN(CCN(CC[N-]1)CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Na+].[Mn+2]

Mn(II)-DO3A Sodium (Cat No.: I040020) is a manganese-based macrocyclic chelate used as a contrast agent in magnetic resonance imaging (MRI) and biomedical research. It offers an alternative to gadolinium-based agents, with potential advantages in safety and biocompatibility. This complex enhances image contrast by shortening T1 relaxation times, making it useful for studying vascular, neurological, and metabolic disorders. The sodium salt improves solubility and stability for in vitro and in vivo applications, making Mn(II)-DO3A a valuable tool in diagnostic imaging and biomedical research.

Reference

[1]. Artali R, et al. Solution thermodynamics, computational and relaxometric studies of ditopic DO3A-based Mn (II) complexes[J]. New Journal of Chemistry, 2015, 39(1): 539-547.