For research use only. Not for therapeutic Use.
Molidustat Sodium Salt (Cat No.:C000721) is a pharmaceutical compound that likely contains solid-state, an investigational medication targeting anemia associated with chronic kidney disease. This sodium salt form enhances solubility and stability. Molidustat functions by inhibiting hypoxia-inducible factor prolyl hydroxylase, leading to increased production of erythropoietin and stimulating red blood cell formation. Research involving Molidustat Sodium Salt focuses on its efficacy in managing anemia, particularly in CKD patients, and its potential benefits in reducing the need for traditional erythropoiesis-stimulating agents. The compound represents a promising avenue for addressing anemia-related complications in renal patients.
| Catalog Number | C000721 |
| CAS Number | 1375799-59-9 |
| Synonyms | 1-[6-(4-Morpholinyl)-4-pyrimidinyl]-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-5-ol Sodium Salt |
| Molecular Formula | C₁₃H₁₃N₈NaO₂ |
| Purity | ≥95% |
| Solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated), Wat |
| Appearance | Pale Orange to Light Orange Solid |
| Storage | 4°C |
| IUPAC Name | sodium;2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)pyrazol-3-olate |
| InChI | InChI=1S/C13H14N8O2.Na/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19;/h1-2,7-9,22H,3-6H2;/q;+1/p-1 |
| InChIKey | VYRQLKYGGSWDNH-UHFFFAOYSA-M |
| SMILES | C1COCCN1C2=NC=NC(=C2)N3C(=C(C=N3)N4C=CN=N4)[O-].[Na+] |
| Reference | Rueger, N., et al.: Mol. Div., 21, 9 (2017); Schmid, H., et al.: Expert Opin. Investig. Drugs, 25, 8 (2016) |
