For research use only. Not for therapeutic Use.
Molnupiravir（Cat No.:I016221）is an antiviral medication used in the treatment of COVID-19. It works by inhibiting the replication of the virus through its incorporation into the viral RNA, leading to errors in the RNA sequence, ultimately preventing the virus from multiplying. Molnupiravir is indicated for use in adults with mild-to-moderate COVID-19 who are at risk of progressing to severe disease. It is taken orally and is often prescribed in combination with other therapeutic measures. The drug shows potential in reducing hospitalization and death rates in at-risk patients.
| Catalog Number | I016221 |
| CAS Number | 2492423-29-5 |
| Molecular Formula | C₁₃H₁₉N₃O₇ |
| Purity | ≥95% |
| Target | SARS-CoV |
| IUPAC Name | [(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(hydroxyamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methyl 2-methylpropanoate |
| InChI | InChI=1S/C13H19N3O7/c1-6(2)12(19)22-5-7-9(17)10(18)11(23-7)16-4-3-8(15-21)14-13(16)20/h3-4,6-7,9-11,17-18,21H,5H2,1-2H3,(H,14,15,20)/t7-,9-,10-,11-/m1/s1 |
| InChIKey | HTNPEHXGEKVIHG-QCNRFFRDSA-N |
| SMILES | CC(C)C(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=NC2=O)NO)O)O |
| Reference | [1]. Sheahan TP, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. Sci Transl Med. 2020 Apr 6. pii: eabb5883.<br>[2]. Toots M, et al. Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Sci Transl Med. 2019 Oct 23;11(515). pii: eaax5866. |
